ISOLATION AND IDENTIFICATION OF ANTIMICROBIAL COMPOUNDS IN BRAZILIAN PROPOLIS

被引:181
作者
AGA, H [1 ]
SHIBUYA, T [1 ]
SUGIMOTO, T [1 ]
KURIMOTO, M [1 ]
NAKAJIMA, S [1 ]
机构
[1] OKAYAMA UNIV, FAC AGR, DEPT BIORESOURCES CHEM, OKAYAMA 700, JAPAN
关键词
D O I
10.1271/bbb.58.945
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three distinct antimicrobial compounds were isolated from Brazilian propolis. These compounds sere identified as 3,5-diprenyl-4-hydroxycinnamic acid (1), 3-prenyl-4-dihydrocinnamoloxycinnamic acid (2), and 2,2-dimethyl-6-carboxyethenyl-2H-1-benzo (3). The respective antimicrobial activity, expressed as MIC is mu g/ml, 1-3 against Bacillus cereus was 15.6, 31.3, and 125; that against Enterobacter aerogenes was 31.3, 62.5, and 125; and that against Arthroderma benhamiae was 15.6, >250, and 62.5. Compound 1 is likely to be one of the major antimicrobial compounds in Brazilian propolis.
引用
收藏
页码:945 / 946
页数:2
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