GENDER EFFECT ON PROGNOSIS OF PATIENTS RECEIVING LONG-TERM HOME OXYGEN-THERAPY

被引：63

作者：

MIYAMOTO, K

AIDA, A

NISHIMURA, M

AIBA, M

KIRA, S

KAWAKAMI, Y

MOHRI, M

KISHI, F

HIDA, W

TAKAHASHI, K

SUZUKI, A

FUKUCHI, Y

KAWASHIRO, T

HORIE, T

KITAMURA, S

KURIYAMA, T

NAKATA, K

TAKAGI, K

SUZUKI, S

KOBAYASHI, T

SUETSUGU, S

KURIHARA, N

KUNO, K

KIMURA, K

SASAKI, T

HIRAMOTO, T

UEDA, N

HIROSE, T

FUKUNAGA, H

MIYAGI, S

机构：

[1] JUNTENDO UNIV,SCH MED,DEPT RESP MED,TOKYO 113,JAPAN

[2] TOKYO UNIV HOSP,TOKYO 113,JAPAN

[3] SAPPORO MINAMI HOSP,SAPPORO,HOKKAIDO,JAPAN

[4] TOHOKU UNIV,DEPT MED 1,SENDAI,MIYAGI 980,JAPAN

[5] YAMAGATA UNIV,DEPT LAB MED,YAMAGATA 990,JAPAN

[6] NIIGATA UNIV,DEPT INTERNAL MED 2,NIIGATA 95021,JAPAN

[7] UNIV TOKYO,DEPT GERIATR,TOKYO,JAPAN

[8] KEIO UNIV,DEPT RESP & CIRCULATORY MED,TOKYO 108,JAPAN

[9] NIHON UNIV,DEPT MED 1,TOKYO 101,JAPAN

[10] CHIBA UNIV,DEPT RESP MED,CHIBA,JAPAN

[11] TORANOMON GEN HOSP,TOKYO,JAPAN

[12] NAGOYA UNIV,DEPT INTERNAL MED 2,NAGOYA,AICHI,JAPAN

[13] YOKOHAMA CITY UNIV,SCH MED,DEPT MED 1,YOKOHAMA,KANAGAWA 232,JAPAN

[14] SHINSHU UNIV,DEPT MED 1,MATSUMOTO,NAGANO 390,JAPAN

[15] OSAKA CITY UNIV,DEPT MED 1,OSAKA 558,JAPAN

[16] KYOTO UNIV,CHEST DIS RES INST,KYOTO,JAPAN

[17] OSAKA HABIKINO HOSP,OSAKA,JAPAN

[18] TORROTI UNIV,DEPT INTERNAL MED 3,TOTTORI,JAPAN

[19] MINAMI FUKUOKA HOSP,FUKUOKA,JAPAN

[20] MINAMI KYUSHU HOSP,TAKANABE,JAPAN

[21] OKINAWA CHUBU HOSP,OKINAWA,JAPAN

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 1995年 / 152卷 / 03期

关键词：

D O I：

10.1164/ajrccm.152.3.7663812

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Although long-term home oxygen therapy (LTOT) certainly prolongs survival, it is not known whether this advantageous effect is similar for both sexes. In this study, we analyzed sex-related differences in survival based on a very large population that had received LTOT from 1986 to 1993. A total of 9,759 patients with chronic obstructive pulmonary disease (COPD), sequelae of tuberculosis (TBsq), and chronic: interstitial pneumonia (IP) were selected in 1,212 medical institutions for analysis of survival rates. The survival rates of both sexes were compared with each other using the Cutler-Ederer method. Despite higher Pa-CO2 at the beginning, the survival rate of women was significantly better than that of men in these three disease categories. Cox's proportional hazards analysis further confirmed the gender effect on survival by eliminating the effects of age, Pa-O2 Pa-CO2 %VC, and FEV(1)/FVC. The mean survival periods of the women who died during follow-up periods were also significantly longer than those of men (0.41 yr in COPD, 1.84 yr in TBsq, and 0.78 yr in IP). From these findings, we conclude women have a better prognosis than men when they start receiving LTOT, regardless of the cause of respiratory failure.

引用

页码：972 / 976

页数：5

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