CHRONIC VARICELLA-ZOSTER VIRUS MYELITIS WITHOUT CUTANEOUS ERUPTION IN A PATIENT WITH AIDS - REPORT OF A FATAL CASE

被引：26

作者：

MANIAN, FA ^{[1
]}

KINDRED, M ^{[1
]}

FULLING, KH ^{[1
]}

机构：

[1] ST JOHNS MERCY MED CTR,DEPT PATHOL,ST LOUIS,MO 63141

来源：

CLINICAL INFECTIOUS DISEASES | 1995年 / 21卷 / 04期

关键词：

D O I：

10.1093/clinids/21.4.986

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe a fatal case of varicella-zoster virus myelitis that was preceded by neurological symptoms for 10 months in a patient with human immunodeficiency virus infection and an extremely low CD4 cell count (20/mu L). The patient was also receiving chronic acyclovir therapy for suppression of herpes simplex. Despite chronic unilateral periauricular and facial pain, which was later accompanied by upper- and lower-extremity weakness, a cutaneous eruption never developed. It is hypothesized that a blunted inflammatory response in the spinal cord-possibly related to a very low CD4 cell count-and long-term acyclovir administration might have contributed to the atypical manifestation of varicella-zoster virus-related neurological disease in this immunocompromised patient.

引用

页码：986 / 988

页数：3

共 9 条

[1] ACUTE VARICELLA-ZOSTER VIRUS VENTRICULITIS AND MENINGO-MYELO-RADICULITIS IN ACQUIRED-IMMUNODEFICIENCY-SYNDROME [J].