THE PKA OF BUTACLAMOL AND THE MODE OF BUTACLAMOL BINDING TO CENTRAL DOPAMINE-RECEPTORS

被引：26

作者：

CHRZANOWSKI, FA

MCGROGAN, BA

MARYANOFF, BE

机构：

[1] MCNEIL PHARMACEUT,DEPT CHEM RES,SPRING HOUSE,PA 19477

[2] MCNEIL PHARMACEUT,BASIC PHARMACEUT SECT,SPRING HOUSE,PA 19477

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1985年 / 28卷 / 03期

关键词：

D O I：

10.1021/jm00381a022

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：399 / 400

页数：2

相关论文

共 23 条

[1] ALBERT A, 1962, IONIZATION CONSTANTS, pCH8
[2] NONLOGARITHMIC TITRATION CURVES FOR DETERMINATION OF DISSOCIATION CONSTANTS AND PURITY
BENET, LZ
GOYAN, JE
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (08) : 1179 - &
[3] NEUROLEPTIC AGENTS OF BENZOCYCLOHEPTAPYRIDOISOQUINOLINE SERIES .1. SYNTHESES AND STEREOCHEMICAL AND STRUCTURAL REQUIREMENTS FOR ACTIVITY OF BUTACLAMOL AND RELATED COMPOUNDS
BRUDERLEIN, FT
HUMBER, LG
VOITH, K
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (02) : 185 - 188
[4] CEPPI E, 1973, TETRAHEDRON LETT, P3627
[5] CHAFFEN LG, 1962, ANAL CHEM, V34, P1495
[6] EVALUATION OF BUTACLAMOL IN CHRONIC-SCHIZOPHRENIC PATIENTS
CLARK, ML
PAREDES, A
COSTILOE, JP
WOOD, F
[J]. JOURNAL OF CLINICAL PHARMACOLOGY, 1977, 17 (8-9) : 529 - 536
[7] FROIMOWITZ M, 1983, MOL PHARMACOL, V24, P243
[8] IONIZATION CONSTANTS AND WATER SOLUBILITIES OF SOME AMINOALKYLPHENOTHIAZINE TRANQUILLIZERS AND RELATED COMPOUNDS
GREEN, AL
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1967, 19 (01) : 10 - &
[9] MAPPING THE DOPAMINE RECEPTOR .1. FEATURES DERIVED FROM MODIFICATIONS IN RING-E OF THE NEUROLEPTIC BUTACLAMOL
HUMBER, LG
BRUDERLEIN, FT
PHILIPP, AH
GOTZ, M
VOITH, K
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (07) : 761 - 767
[10] INAZ F, 1976, PSYCHOPHARMACOL B, V12, P31