SHEAR-STRESS RELATED BLOOD DAMAGE ALONG THE CUSP OF A TRI-LEAFLET PROSTHETIC VALVE

被引：3

作者：

EINAV, S ^{[1
]}

REUL, H ^{[1
]}

RAU, G ^{[1
]}

ELAD, D ^{[1
]}

机构：

[1] RHEIN WESTFAL TH AACHEN,HELMHOLTZ INST BIOMED TECH,W-5100 AACHEN,GERMANY

来源：

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS | 1991年 / 14卷 / 11期

关键词：

PROSTHETIC HEART VALVE; BLOOD DAMAGE; SHEAR STRESS; BLOOD-SURFACE INTERACTION;

D O I：

10.1177/039139889101401107

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Blood flowing through a prosthetic heart valve can be damaged by flow-induced shear forces. Fluid dynamics variables and geometric factors play an important role in the evaluation of shear-stress-related blood damage. Central-flow prosthetic valves have been considered as an optimal replacement for mechanical and biological valves. Recently it was shown that shear stress distribution along the surface of a polyurethane cusp reaches values that can damage the blood elements. A mathematical model correlating the effects of shear stresses on blood corpuscles with clinical findings was employed in vitro. The model can be applied to the effects of blood-surface interaction and is of clinical relevance.

引用

页码：716 / 720

页数：5

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