MAST-CELL DIFFERENTIATION ANTIGENS - EXPRESSION IN NORMAL AND MALIGNANT-CELLS AND USE FOR DIAGNOSTIC PURPOSES

被引：28

作者：

VALENT, P

机构：

[1] Department of Internal Medicine I, Division of Hematology, University of Vienna, Vienna

来源：

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 1995年 / 25卷 / 10期

关键词：

C-KIT; HISTAMINE; LEUKEMIA; MAST CELLS; MGF; TRYPTASE;

D O I：

10.1111/j.1365-2362.1995.tb01948.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antibodies against haemopoietic differentiation antigens are widely used for the identification and classification of leukaemic cells. Mast cells are distinct haemopoietic cells and express a unique composition of antigens. They can be differentiated from basophils and all other lymphohaemopoietic cells by using antibodies to cell surface receptors and granular mediator molecules. This paper provides evidence that antibodies against mast cell antigens can be used to identify and classify malignant cell populations in patients with mastocytosis.

引用

页码：715 / 720

页数：6

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