THE CEPH CONSORTIUM LINKAGE MAP OF HUMAN CHROMOSOME-2

被引：19

作者：

SPURR, NK

COX, S

BRYANT, SP

ATTWOOD, J

ROBSON, EB

SHIELDS, DC

STEINBRUECK, T

JENKINS, T

MURRAY, JC

KIDD, KK

SUMMAR, ML

TSIPOURAS, P

RETIEF, AE

KRUSE, TA

BALE, AE

VERGNAUD, G

WEBER, JL

MCBRIDE, OW

DONISKELLER, H

WHITE, RL

机构：

[1] UNIV LONDON UNIV COLL,MRC,HUMAN BIOCHEM GENET UNIT,GALTON LAB,LONDON NW1 2HE,ENGLAND

[2] PRINCESS ANNE HOSP,DEPT CHILD HLTH,CRC GENET EPIDEMIOL RES GRP,SOUTHAMPTON SO9 4HA,ENGLAND

[3] WASHINGTON UNIV,SCH MED,DEPT GENET,ST LOUIS,MO 63110

[4] S AFRICAN INST MED RES,SCH PATHOL,DEPT HUMAN GENET,MRC,HUMAN ECOGENET RES UNIT,JOHANNESBURG 2000,SOUTH AFRICA

[5] UNIV WITWATERSRAND,JOHANNESBURG 2001,SOUTH AFRICA

[6] UNIV IOWA,DEPT PEDIAT,IOWA CITY,IA 52242

[7] YALE UNIV,SCH MED,DEPT HUMAN GENET,NEW HAVEN,CT 06510

[8] VANDERBILT UNIV,MED CTR,DEPT PEDIAT,NASHVILLE,TN 37232

[9] UNIV CONNECTICUT,CTR HLTH,DEPT PEDIAT,MOLEC GENET LAB,FARMINGTON,CT 06032

[10] UNIV STELLENBOSCH,STELLENBOSCH 7600,SOUTH AFRICA

[11] AARHUS UNIV,BARTOLIN BYGNINGEN,INST HUMAN GENET,DK-8000 AARHUS,DENMARK

[12] CTR ETUD BOUCHET,F-91710 VERT LE PETIT,FRANCE

[13] MARSHFIELD MED RES FDN,MARSHFIELD,WI 54449

[14] NCI,BIOCHEM LAB,BETHESDA,MD 20892

[15] UNIV UTAH,HOWARD HUGHES MED INST,SALT LAKE CITY,UT 84132

[16] UNIV LONDON UNIV COLL,DEPT GENET & BIOMETRY,GALTON LAB,LONDON NW1 2HE,ENGLAND

来源：

GENOMICS | 1992年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0888-7543(05)80129-6

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

This paper describes the Centre d'Etude du Polymorphisme Humain (CEPH) consortium linkage map of chromosome 2. The map contains 36 loci defined by genotyping generated from the CEPH family DNAs. A total of 73 different markers were typed by 14 contributing laboratories; of these, 36 loci are ordered on the map with likelihood support of at least 1000:1. Markers are placed along the length of the chromosome but no markers were available to anchor the map at either telomere or the centromere. Multilocus linkage analysis has produced male, female, and sex-averaged maps extending for 261, 430, and 328 cM, respectively. The sex-averaged map contains five intervals greater than 15 cM and the mean genetic distance between the 36 uniquely placed loci is 9.1 cM. © 1992 Academic Press, Inc. All rights reserved.

引用

页码：1055 / 1063

页数：9

共 25 条

[1]

ARDINGER HH, 1989, AM J HUM GENET, V45, P348

[2]

ASHER JH, 1991, AM J HUM GENET, V48, P43

[3] AN EXONIC MUTATION IN THE HUP2 PAIRED DOMAIN GENE CAUSES WAARDENBURG SYNDROME [J].

BALDWIN, CT ;

HOTH, CF ;

AMOS, JA ;

DASILVA, EO ;

MILUNSKY, A .

NATURE, 1992, 355 (6361) :637-638

[4] STRUCTURE AND POLYMORPHISM OF HUMAN TELOMERE-ASSOCIATED DNA [J].

BROWN, WRA ;

MACKINNON, PJ ;

VILLASANTE, A ;

SPURR, N ;

BUCKLE, VJ ;

DOBSON, MJ .

CELL, 1990, 63 (01) :119-132

[5]

BUETOW KH, 1991, AM J HUM GENET, V49, P985

[6] PROGRAM DESCRIPTION - CENTER-DETUDE-DU-POLYMORPHISME-HUMAIN (CEPH) - COLLABORATIVE GENETIC-MAPPING OF THE HUMAN GENOME [J].

DAUSSET, J ;

CANN, H ;

COHEN, D ;

LATHROP, M ;

LALOUEL, JM ;

WHITE, R .

GENOMICS, 1990, 6 (03) :575-577

[7] A GENETIC-LINKAGE MAP OF THE HUMAN GENOME [J].

DONISKELLER, H ;

GREEN, P ;

HELMS, C ;

CARTINHOUR, S ;

WEIFFENBACH, B ;

STEPHENS, K ;

KEITH, TP ;

BOWDEN, DW ;

SMITH, DR ;

LANDER, ES ;

BOTSTEIN, D ;

AKOTS, G ;

REDIKER, KS ;

GRAVIUS, T ;

BROWN, VA ;

RISING, MB ;

PARKER, C ;

POWERS, JA ;

WATT, DE ;

KAUFFMAN, ER ;

BRICKER, A ;

PHIPPS, P ;

MULLERKAHLE, H ;

FULTON, TR ;

NG, S ;

SCHUMM, JW ;

BRAMAN, JC ;

KNOWLTON, RG ;

BARKER, DF ;

CROOKS, SM ;

LINCOLN, SE ;

DALY, MJ ;

ABRAHAMSON, J .

CELL, 1987, 51 (02) :319-337

[8] THE CEPH1 CONSORTIUM LINKAGE MAP OF HUMAN CHROMOSOME-1 [J].

DRACOPOLI, NC ;

OCONNELL, P ;

ELSNER, TI ;

LALOUEL, JM ;

WHITE, RL ;

BUETOW, KH ;

NISHIMURA, DY ;

MURRAY, JC ;

HELMS, C ;

MISHRA, SK ;

DONISKELLER, H ;

HALL, JM ;

LEE, MK ;

KING, MC ;

ATTWOOD, J ;

MORTON, NE ;

ROBSON, EB ;

MAHTANI, M ;

WILLARD, HF ;

ROYLE, NJ ;

PATEL, I ;

JEFFREYS, AJ ;

VERGA, V ;

JENKINS, T ;

WEBER, JL ;

MITCHELL, AL ;

BALE, AE .

GENOMICS, 1991, 9 (04) :686-700

[9]

FOY C, 1990, AM J HUM GENET, V46, P1017

[10] ORIGIN OF HUMAN CHROMOSOME-2 - AN ANCESTRAL TELOMERE TELOMERE FUSION [J].

IJDO, JW ;

BALDINI, A ;

WARD, DC ;

REEDERS, ST ;

WELLS, RA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (20) :9051-9055

← 1 2 3 →