DIDEMNILACTONE-A AND DIDEMNILACTONE-B AND NEODIDEMNILACTONE, 3 NEW FATTY-ACID METABOLITES ISOLATED FROM THE TUNICATE DIDEMNUM MOSELEYI (HERDMAN)

被引：19

作者：

NIWA, H

WATANABE, M

INAGAKI, H

YAMADA, K

机构：

[1] Department of Chemistry, Faculty of Science, Nagoya University, Chikusa, Nagoya

来源：

TETRAHEDRON | 1994年 / 50卷 / 25期

关键词：

D O I：

10.1016/S0040-4020(01)90469-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new fatty acid metabolites didemnilactones A (1) and B (2) and neodidemnilactone (3) were isolated from the tunicate Didemnum moseleyi (Herdman). Their structures including absolute stereochemistry were established on the basis of spectral studies and chemical synthesis. Didemnilactones exhibited inhibitory activity against lipoxygenase and weak binding activity to leukotriene B-4 receptors.

引用

页码：7385 / 7400

页数：16

共 21 条

[1] REACTIONS OF ALKYLIDENETRIPHENYLPHOSPHORANES .33. PREPARATIONS OF LITHIUM SALTFREE YLID SOLUTIONS WITH SODIUM BIS(TRIMETHYLSILYL)AMIDE AS BASE [J].