SPATIAL DISORDERS AND COMPUTATIONAL CURES

被引：5

作者：

STEVEN, AC

KOCSIS, E

UNSER, M

TRUS, BL

机构：

[1] NIAMSD, STRUCT BIOL RES LAB, BETHESDA, MD 20892 USA

[2] NATL CTR RES RESOURCES, BIOMED ENGN & INSTRUMENTAT PROGRAM, BETHESDA, MD 20892 USA

[3] NIH, DIV COMP RES & TECHNOL, COMP SYST LAB, BETHESDA, MD 20892 USA

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 1991年 / 13卷 / 03期

基金：

美国国家卫生研究院;

关键词：

DIGITAL IMAGE PROCESSING; BIOLOGICAL ELECTRON MICROSCOPY; SPATIAL DISORDER; PROTEIN CRYSTALS; CURVILINEAR COORDINATES; CORRELATION AVERAGING; MULTIVARIATE STATISTICS;

D O I：

10.1016/0141-8130(91)90044-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Image averaging provides a powerful method for enhancing the yield of interpretable information from electron micrographs of biological macromolecules. However, as originally conceived, the full benefit of averaging is achieved only with perfectly ordered two-dimensional crystals. More recent developments, reviewed here, allow one to rectify disordered lattices, straighten randomly bent filaments, and combine multiple images of free-standing particles, thus extending the advantages of image averaging to virtually every class of macromolecular specimen.

引用

页码：174 / 180

页数：7

共 40 条

[1]

AEBI U, 1989, CYTOSKELETAL EXTRACE

[2] THE RECONSTRUCTION OF HELICAL PARTICLES WITH VARIABLE PITCH [J].