ENZYMATIC AMPLIFICATION OF BETA-GLOBIN GENOMIC SEQUENCES AND RESTRICTION SITE ANALYSIS FOR DIAGNOSIS OF SICKLE-CELL ANEMIA

被引：7710

作者：

SAIKI, RK

SCHARF, S

FALOONA, F

MULLIS, KB

HORN, GT

ERLICH, HA

ARNHEIM, N

机构：

[1] Department of Human Genetics, Cetus Corporation, Emeryville, CA 94608, United States

来源：

SCIENCE | 1985年 / 230卷 / 4732期

关键词：

D O I：

10.1126/science.2999980

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1350 / 1354

页数：5

共 19 条

[1] A SENSITIVE NEW PRENATAL TEST FOR SICKLE-CELL-ANEMIA [J].

CHANG, JC ;

KAN, YW .

NEW ENGLAND JOURNAL OF MEDICINE, 1982, 307 (01) :30-32

[2] DETECTION OF SICKLE-CELL BETA-S-GLOBIN ALLELE BY HYBRIDIZATION WITH SYNTHETIC OLIGONUCLEOTIDES [J].

CONNER, BJ ;

REYES, AA ;

MORIN, C ;

ITAKURA, K ;

TEPLITZ, RL ;

WALLACE, RB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (01) :278-282

[3] PRENATAL DIAGNOSIS OF HOMOZYGOUS ALPHA-THALASSEMIA [J].

DOZY, AM ;

FORMAN, EN ;

ABUELO, DN ;

BARSELBOWERS, G ;

MAHONEY, MJ ;

FORGET, BG ;

KAN, YW .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1979, 241 (15) :1610-1612

[4]

ELLIS KP, 1985, BIOCHEM J, V226, P1

[5]

FALOONA F, UNPUB

[6] DIRECT IDENTIFICATION OF SICKLE-CELL-ANEMIA BY BLOT HYBRIDIZATION [J].

GEEVER, RF ;

WILSON, LB ;

NALLASETH, FS ;

MILNER, PF ;

BITTNER, M ;

WILSON, JT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (08) :5081-5085

[7] PRENATAL DIAGNOSIS OF ALPHA-THALASSEMIA - CLINICAL APPLICATION OF MOLECULAR HYBRIDIZATION [J].

KAN, YW ;

GOLBUS, MS ;

DOZY, AM .

NEW ENGLAND JOURNAL OF MEDICINE, 1976, 295 (21) :1165-1167

[8] ALPHA-1-ANTITRYPSIN DEFICIENCY DETECTION BY DIRECT ANALYSIS OF THE MUTATION IN THE GENE [J].

KIDD, VJ ;

WALLACE, RB ;

ITAKURA, K ;

WOO, SLC .

NATURE, 1983, 304 (5923) :230-234

[9] DETECTION OF SINGLE BASE SUBSTITUTIONS IN TOTAL GENOMIC DNA [J].

MYERS, RM ;

LUMELSKY, N ;

LERMAN, LS ;

MANIATIS, T .

NATURE, 1985, 313 (6002) :495-498

[10] IMPROVED DETECTION OF THE SICKLE MUTATION BY DNA ANALYSIS - APPLICATION TO PRENATAL-DIAGNOSIS [J].

ORKIN, SH ;

LITTLE, PFR ;

KAZAZIAN, HH ;

BOEHM, CD .

NEW ENGLAND JOURNAL OF MEDICINE, 1982, 307 (01) :32-36

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