BIOLOGICAL ROLES OF NITRIC-OXIDE

被引:501
作者
SNYDER, SH
BREDT, DS
机构
[1] Department of Neuroscience, Johns Hopkins Univ. School of Med., Baltimore
关键词
D O I
10.1038/scientificamerican0592-68
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
One of the body's most versatile regulatory chemicals is not a complex protein but a simple, highly toxic inorganic molecule that persists for less than 10 seconds. Nitric oxide transmits messages between neutrons, signals blood vessels to dilate and is the weapon of white blood cells against tumors and bacteria. Its intricate physiological functions have been revealed over the past five years.
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页码:68 / &
相关论文
共 5 条
[1]   CLONED AND EXPRESSED NITRIC-OXIDE SYNTHASE STRUCTURALLY RESEMBLES CYTOCHROME-P-450 REDUCTASE [J].
BREDT, DS ;
HWANG, PM ;
GLATT, CE ;
LOWENSTEIN, C ;
REED, RR ;
SNYDER, SH .
NATURE, 1991, 351 (6329) :714-718
[2]  
Bredt DS, 1992, NEURON, V8, P3
[3]   THE OBLIGATORY ROLE OF ENDOTHELIAL-CELLS IN THE RELAXATION OF ARTERIAL SMOOTH-MUSCLE BY ACETYLCHOLINE [J].
FURCHGOTT, RF ;
ZAWADZKI, JV .
NATURE, 1980, 288 (5789) :373-376
[4]  
MONCADA S, 1991, PHARMACOL REV, V43, P109
[5]  
MONCADA S, 1990, NITRIC OXIDE L ARGIN