SPARSE DATA-ANALYSIS

被引：25

作者：

AARONS, L

机构：

[1] Pharmacy Department, University of Manchester, Manchester, M13 9PL, Oxford Road

来源：

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS | 1993年 / 18卷 / 01期

关键词：

SPARSE DATA ANALYSIS; POPULATION PHARMACOKINETICS; PHARMACODYNAMICS; NONMEM; DRUG DEVELOPMENT;

D O I：

10.1007/BF03220012

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In recent years there has been a growing interest in techniques capable of analyzing sparse data, particularly gathered during Phase III clinical trials, and there is now pressure on manufacturers to obtain more kinetic and dynamic information from Phase III studies. Techniques for the analysis of sparse data are reviewed drawing on a number of examples taken from pharmacokinetic and pharmacodynamic experiments.

引用

页码：97 / 100

页数：4

共 30 条

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