CIRCADIAN VARIATION IN THE FREQUENCY OF ISCHEMIC STROKE

被引：132

作者：

ARGENTINO, C ^{[1
]}

TONI, D ^{[1
]}

RASURA, M ^{[1
]}

VIOLI, F ^{[1
]}

SACCHETTI, ML ^{[1
]}

ALLEGRETTA, A ^{[1
]}

BALSANO, F ^{[1
]}

FIESCHI, C ^{[1
]}

机构：

[1] UNIV ROME LA SAPIENZA,INST MED CLIN 1,I-00185 ROME,ITALY

来源：

STROKE | 1990年 / 21卷 / 03期

关键词：

Cerebral ischemia; Cerebrovascular disorders; Circadian rhythm;

D O I：

10.1161/01.STR.21.3.387

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The frequency of myocardial infarction and sudden death is increased between 6 AM and noon. To determine whether the same is true for the onset of ischemic stroke, we studied 426 consecutive patients within 12 hours after the onset of their first hemispheric stroke. The frequency of onset of hemispheric stroke was significantly (p=0.0001) higher from 6:01 AM to noon (56.1%) than from 12:01 PM to 6 PM (20.2%), from 6:01 PM to midnight (8.2%), and from 12:01 AM to 6 AM (15.5%). The identification of periods of high risk for vascular events may have important therapeutic implications, such as matching drug effects with vulnerability. © 1990 American Heart Association, Inc.

引用

页码：387 / 389

页数：3

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