SIGNAL TRANSDUCTION IN YEAST MATING - RECEPTORS, TRANSCRIPTION FACTORS, AND THE KINASE CONNECTION

被引：68

作者：

SPRAGUE, GF ^{[1
]}

机构：

[1] UNIV OREGON,DEPT BIOL,EUGENE,OR 97403

来源：

TRENDS IN GENETICS | 1991年 / 7卷 / 11-12期

关键词：

D O I：

10.1016/0168-9525(91)90262-O

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. Binding of pheromone to G-protein-coupled receptors activates a cascade of serine/threonine protein kinases that ultimately phosphorylate and increase the activity of an identified transcription factor.

引用

页码：393 / 398

页数：6

共 44 条

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