APPLICATIONS OF REDOX POLYMERS IN BIOSENSORS

被引：11

作者：

BOGUSLAVSKY, L ^{[1
]}

HALE, PD ^{[1
]}

GENG, L ^{[1
]}

SKOTHEIM, TA ^{[1
]}

LEE, HS ^{[1
]}

机构：

[1] BROOKHAVEN NATL LAB, DEPT APPL SCI, UPTON, NY 11973 USA

来源：

SOLID STATE IONICS | 1993年 / 60卷 / 1-3期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0167-2738(93)90294-D

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Polymers containing covalently attached redox molecules can be highly effective electron transfer mediators for flavin adenine dinucleotide redox centers of many oxidases. Highly flexible siloxane and ethylene oxide polymers containing covalently attached ferrocene molecules are shown to be capable of mediating electron transfer between enzymes and an electrode. The construction and response of bienzyme cholesterol biosensor, acetylcholine and glucose biosensor are described and discussed. Our data showed that the flexibility, hydrophilicity of the polymer, the density of redox centers in the polymer matrices and the self-exchange reaction rate of the redox molecules control the efficiency of the electron transfer mediation.

引用

页码：189 / 197

页数：9

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