THE ROLE OF THE HYDROGEN-BOND AND WATER IN BIOLOGICAL PROCESSES

被引：25

作者：

JEFFREY, GA

机构：

[1] Department of Crystallography, University of Pittsburgh, Pittsburgh

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1994年 / 322卷

关键词：

D O I：

10.1016/0022-2860(94)87017-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Water plays a role in biological systems both as a packing molecule and as an attenuator of strong hydrogen bonds which might otherwise restrict conformational flexibility. It is suggested that the non-additivity or cooperative property of chains of hydroxy bonds can provide a steering component to add to the ''lock and key'' analogy of substrate-receptor interactions.

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页码：21 / 25

页数：5

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