PLASMACYTOMA OF THE NASAL CAVITY WITH LAMBDA-III AMYLOID DEPOSITION

被引：7

作者：

EILAM, O

LIEPNIEKS, JJ

WEISBERGER, E

BENSON, MD

机构：

[1] INDIANA UNIV,SCH MED,DEPT MED,INDIANAPOLIS,IN 46202

[2] INDIANA UNIV,SCH MED,DEPT MED & MOLEC GENET,INDIANAPOLIS,IN 46202

[3] RICHARD L ROUDEBUSH VET AFFAIRS MED CTR,INDIANAPOLIS,IN 46202

来源：

AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION | 1995年 / 2卷 / 01期

关键词：

PLASMACYTOMA; LOCALIZED AMYLOIDOSIS; LAMBDA III LIGHT CHAIN; UPPER RESPIRATORY TRACT;

D O I：

10.3109/13506129509031885

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A patient presented with a large nasal plasmacytoma that involved the palate, ethmoid and maxillary sinuses and contained deposits of amyloid. Immunoglobulin (AL) amyloid was found in the tumor. Amyloid fibrils extracted from the resected tumor were found to contain lambda light chain protein. Complete sequence analysis identified the protein as lambda III immunoglobulin light chain. Evaluation of the patient failed to reveal any sign of systemic amyloidosis and three years of follow-up has shown no evidence of recurrence.

引用

页码：31 / 35

页数：5

共 24 条

[1]

BATERAKIS JG, 1983, ANN OTO RHINOL LARYN, V92, P311

[2] LOCALIZED AMYLOIDOSIS OF THE LARYNX - EVIDENCE FOR LIGHT-CHAIN COMPOSITION [J].