PROGRESSIVE LOSS OF SPEECH OUTPUT AND OROFACIAL DYSPRAXIA ASSOCIATED WITH FRONTAL-LOBE HYPOMETABOLISM

被引：63

作者：

TYRRELL, PJ

KARTSOUNIS, LD

FRACKOWIAK, RSJ

FINDLEY, LJ

ROSSOR, MN

机构：

[1] ST MARYS HOSP,DEPT NEUROL,ALZHEIMERS DIS RES GRP,PRAED ST,LONDON W2 1NY,ENGLAND

[2] HAMMERSMITH HOSP,MRC,CYCLOTRON UNIT,LONDON W12 0HS,ENGLAND

[3] NATL HOSP,LONDON WC1N 3BG,ENGLAND

[4] OLDCHURCH HOSP,ROMFORD RM7 0BE,ESSEX,ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1991年 / 54卷 / 04期

关键词：

D O I：

10.1136/jnnp.54.4.351

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Three patients are described with slowly progressive loss of speech and dysarthria associated with orofacial dyspraxia, initially with intact written language, who subsequently developed more widespread cognitive abnormalities. Positron emission tomography (PET) revealed bifrontal hypometabolism in all of the patients, most marked in the inferior and lateral portions of both frontal lobes, with some extension into the parietal and temporal cortices in one case. These patients may represent a further example of focal progressive cortical degeneration.

引用

页码：351 / 357

页数：7

共 48 条

[1]

BAXTER DM, 1987, THESIS U LONDON

[2] POSTERIOR CORTICAL ATROPHY [J].