MAGNETIC-RESONANCE-IMAGING IN CHILDREN RECEIVING QUINOLONES - NO EVIDENCE OF QUINOLONE-INDUCED ARTHROPATHY A MULTICENTER SURVEY

被引：32

作者：

DANISOVICOVA, A

BREZINA, M

BELAN, S

KAYSEROVA, H

KAISEROVA, E

HRUSKOVIC, I

OROSOVA, K

DLUHOLUCKY, S

GALOVA, K

MATHEOVA, E

MARINOVA, I

KRCMERY, V

机构：

[1] HOSP BANSKA BYSTRICA & KOSICE,DEPT PEDIAT NURSING,KOSICE,SLOVAKIA

[2] HOSP BANSKA BYSTRICA & KOSICE,DEPT PEDIAT,KOSICE,SLOVAKIA

[3] HOSP BANSKA BYSTRICA & KOSICE,DEPT RADIOL,KOSICE,SLOVAKIA

[4] HOSP BANSKA BYSTRICA & KOSICE,POSTGRAD MED SCH,DEPT ONCOL,KOSICE,SLOVAKIA

[5] UNIV TYRNAVIENSIS,DEPT PREVENT MED,BRATISLAVA,SLOVAKIA

[6] POSTGRAD MED SCH & MED FAC,DEPT CHEMOTHERAPY,BRATISLAVA,SLOVAKIA

来源：

CHEMOTHERAPY | 1994年 / 40卷 / 03期

关键词：

QUINOLONE-ASSOCIATED ARTHROPATHY; CIPROFLOXACIN; OFLOXACIN; MAGNETIC RESONANCE IMAGING;

D O I：

10.1159/000239194

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twenty-nine children with cystic fibrosis (CF) were investigated for quinolone-induced arthropathy. Magnetic resonance imaging (MRI) was performed in 14/14 children treated with ofloxacin or ciprofloxacin and in 10/15 of those never treated with quinolones. The frequency of pathologic MRI findings, concerning cartilage thickness, careful analysis of the cartilage structure, presence of edema, cartilage-bone borderline and the presence of fluid in joints did not show any difference between both groups. Thus the presence of quinolone-induced arthrotoxicity cannot be confirmed in this study.

引用

页码：209 / 214

页数：6

共 12 条

[1] SAFETY OF CIPROFLOXACIN IN CHILDREN - WORLDWIDE CLINICAL-EXPERIENCE BASED ON COMPASSIONATE USE - EMPHASIS ON JOINT EVALUATION [J].