HEMOGLOBIN HACETTEPE OR ALPHA-2BETA-2-127(HS)GLN-]GLU

被引：12

作者：

ALTAY, C

ALTINOZ, N

WILSON, JB

BOLCH, KC

HUISMAN, THJ

机构：

[1] HACETTEPE UNIV, SCH MED, DEPT PEDIAT, ANKARA, TURKEY

[2] MED COLL GEORGIA, PROT CHEM LAB, AUGUSTA, GA 30902 USA

[3] MED COLL GEORGIA, CTR COMPREHENS SICKLE CELL, DEPT CELL & MOLEC BIOL, AUGUSTA, GA 30902 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1976年 / 434卷 / 01期

关键词：

D O I：

10.1016/0005-2795(76)90029-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hb-Hacettepe was observed in a father and daughter from S Turkey. The variant had a substitution in position 127 of the .beta. chain and the normally occurring glutaminyl residue was replaced by a glutamyl residue. The presence of this variant did not have clinical consequences.

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页码：1 / 3

页数：3

相关论文

共 17 条

[1] HEMOGLOBIN-E SYNDROMES .1. HEMOGLOBIN-E IN ETI-TURKS [J].

AKSOY, M .

BLOOD, 1960, 15 (05) :606-609

[2] HEMOGLOBIN S IN ETI-TURKS AND ALLEWITS IN LEBANON [J].

AKSOY, M .

BLOOD, 1961, 17 (05) :657-&

[3] SEPARATION OF ALPHA AND BETA-CHAINS OF HUMAN HAEMOGLOBIN [J].

CLEGG, JB ;

NAUGHTON, MA ;

WEATHERALL, DJ .

NATURE, 1968, 219 (5149) :69-+

[4]

COHEN OW, 1972, NATURE, V243, P467

[5] STUDIES ON HETEROGENEITY OF HEMOGLOBIN .13. CHROMATOGRAPHY OF VARIOUS HUMAN AND ANIMAL HEMOGLOBIN TYPES ON DEAE-SEPHADEX [J].

DOZY, AM ;

KLEIHAUER, EF ;

HUISMAN, THJ .

JOURNAL OF CHROMATOGRAPHY, 1968, 32 (04) :723-+

[6]

EFREMOV GD, 1974, CLIN HAEMATOL, V3, P527

[7]

EFREMOV GD, 1969, J BIOL CHEM, V244, P6105

[8] CONGENITAL HEINZ-BODY ANAEMIA - FURTHER EVIDENCE ON CAUSE OF HEINZ-BODY PRODUCTION IN RED CELLS [J].

GRIMES, AJ ;

MEISLER, A ;

DACIE, JV .

BRITISH JOURNAL OF HAEMATOLOGY, 1964, 10 (03) :281-&

[9] HB CAMDEN AND HB HOPE FOUND DURING ROUTINE TESTING [J].

HUBBARD, M ;

WILSON, JB ;

WRIGHTSTONE, RN ;

EFREMOV, GD ;

HUISMAN, THJ .

ACTA HAEMATOLOGICA, 1975, 54 (01) :53-58

[10] STUDIES ON HETEROGENEITY OF HEMOGLOBIN .9. USE OF TRIS(HYDROXYMETHYL)AMINOMETHANE-HC1 BUFFERS IN ANION-EXCHANGE CHROMATOGRAPHY OF HEMOGLOBINS [J].

HUISMAN, THJ ;

DOZY, AM .

JOURNAL OF CHROMATOGRAPHY, 1965, 19 (01) :160-&