HYPEREOSINOPHILIC SYNDROME ACCOMPANIED WITH NECROSIS OF FINGER TIPS

被引：18

作者：

TAKEKAWA, M ^{[1
]}

IMAI, K ^{[1
]}

ADACHI, M ^{[1
]}

AOKI, S ^{[1
]}

MAEDA, K ^{[1
]}

HINODA, Y ^{[1
]}

YACHI, A ^{[1
]}

机构：

[1] SAPPORO MED COLL,DEPT INTERNAL MED,SECT 1,S-1 W-16,CHUO KU,SAPPORO,HOKKAIDO 060,JAPAN

来源：

INTERNAL MEDICINE | 1992年 / 31卷 / 11期

关键词：

CHURG-STRAUSS SYNDROME; EOSINOPHILIA; COLLAGEN DISEASE; STEROID THERAPY; TNF;

D O I：

10.2169/internalmedicine.31.1262

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of hypereosinophilic syndrome (HES) with marked eosinophilia (59.7%) and mononeuritis multiplex (upper limbs and buttocks). Necrosis of the finger tips was the primary manifestation which simultaneously occurred on both sides. These clinical manifestations were improved dramatically by subsequent steroid therapy. Interestingly, an elevation of serum tumor necrosis factor (TNF) was observed. These findings suggest that TNF may play a role in the etiology of necrosis of the finger tips.

引用

页码：1262 / 1266

页数：5

共 13 条

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