ISOLATION OF A HIGHLY FUNCTIONALIZED TROGER BASE DERIVATIVE VIA A NOVEL REACTION

被引：33

作者：

BECKER, DP

FINNEGAN, PM

COLLINS, PW

机构：

[1] Searle Research and Development, Skokie, IL 60077

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(00)91955-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heating a solution of methyl 5-chloro-4-[(ethoxyoxoacctyl)amino]-2-methoxybenz-oate 3 in DMSO gave rise to the formation of the highly substituted Troger's base derivative dimethyl 4,10-dichloro-1,7-dimethoxy-6H,12H-5,11-methano-dibenzo[b,f][1,5]diazocine-2,8-dicarboxylate 4 as well as methyl 8-chloro-5-methoxy-6-quinolinecarboxylate 5.

引用

页码：1889 / 1892

页数：4

共 17 条

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