PROLONGED EXPOSURE TO SUBMICROMOLAR CONCENTRATIONS OF QUINOLINIC ACID CAUSES EXCITOTOXIC DAMAGE IN ORGANOTYPIC CULTURES OF RAT CORTICOSTRIATAL SYSTEM

被引：167

作者：

WHETSELL, WO ^{[1
]}

SCHWARCZ, R ^{[1
]}

机构：

[1] MARYLAND PSYCHIAT RES CTR,BALTIMORE,MD 21228

来源：

NEUROSCIENCE LETTERS | 1989年 / 97卷 / 03期

关键词：

D O I：

10.1016/0304-3940(89)90609-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：271 / 275

页数：5

共 11 条

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[3] QUINOLINIC ACID - AN ENDOGENOUS METABOLITE THAT PRODUCES AXON-SPARING LESIONS IN RAT-BRAIN [J].

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[4] EXCITOTOXIC MODELS FOR NEURODEGENERATIVE DISORDERS [J].

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LIFE SCIENCES, 1984, 35 (01) :19-32

[5] 3-HYDROXYANTHRANILATE OXYGENASE ACTIVITY IS INCREASED IN THE BRAINS OF HUNTINGTON DISEASE VICTIMS [J].

SCHWARCZ, R ;

OKUNO, E ;

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WHETSELL, WO .

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[6]

Schwarcz R., 1987, P19

[7]

Schwarcz R., 1987, ANIMAL MODELS DEMENT, P39

[8]

WHETSELL WO, 1983, EXCITOTOXINS, P207

[9]

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[10]

WHETSELL WO, 1979, ADV NEUROL, V23, P645

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