SYNTHESIS OF STATINE FROM (S)-MALIC ACID - STEREOCONTROL VIA RADICAL CYCLIZATION

被引：105

作者：

KOOT, WJ

VANGINKEL, R

KRANENBURG, M

HIEMSTRA, H

LOUWRIER, S

MOOLENAAR, MJ

SPECKAMP, WN

机构：

[1] Department of Organic Chemistry, University of Amsterdam, 1018 WS Amsterdam

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 03期

关键词：

D O I：

10.1016/S0040-4039(00)92639-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly stereoselective syntheses of enantiomerically pure gamma-amino acids statine and 4-epistatine from (S)-malic acid are described by using, respectively, an intramolecular alpha-acylamino radical reaction and an intermolecular N-acyliminium allylsilane coupling.

引用

页码：401 / 404

页数：4

共 36 条

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