IMMUNOHISTOCHEMISTRY IN THE DIAGNOSIS OF MALIGNANT-MELANOMA

被引：8

作者：

SMOLLER, BR

机构：

[1] Department of Pathology and Dermatology, Stanford University Medical Center, Stanford, CA

来源：

CLINICS IN DERMATOLOGY | 1991年 / 9卷 / 02期

关键词：

D O I：

10.1016/0738-081X(91)90013-B

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

There are two major roles for immunohistochemistry in diagnosing melanocytic lesions. The first, and presently more successful role, is that of determining the melanocytic nature of a given tumor and of excluding other non-melanocytic histologic simulants. The second role for the immunoperoxidase methodology involves helping define the potential biologic behavior of a given lesion, once its melanocytic origin has been demonstrated. This objective remains largely elusive, as will be discussed more fully below. This chapter will outline a strategy for using immunohistochemistry to characterize tumors as being of melanocytic origin, with a brief discussion of antibodies employed toward this end. Following this, antibodies directed specifically against melanoma cells, as opposed to melanocytes in general, will be discussed and evaluated. © 1991.

引用

页码：235 / 241

页数：7

共 49 条

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