SPECTROPHOTOMETRIC DETERMINATION OF STREPTOMYCIN

被引：26

作者：

AMAN, T

RASHID, A

KULSOOM, R

KHOKHAR, I

机构：

[1] GOVT COLL,DEPT CHEM,LAHORE,PAKISTAN

[2] PUNJAB UNIV,DEPT CHEM,LAHORE,PAKISTAN

来源：

ANALYTICAL LETTERS | 1995年 / 28卷 / 05期

关键词：

SPECTROPHOTOMETER; STREPTOMYCIN; NINHYDRIN;

D O I：

10.1080/00032719508001431

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Streptomycin reacts with ninhydrin in alkaline medium to give a violet colour having maximum absorbance at 560 nm. The reaction is specific for streptomycin with 0.1 mu g/ml as minimum limit of detection. It also provides the basis for a new spectrophotometric determination of pure streptomycin and in the presence of the organic compounds. The maximum tolerable limits of these are reported. The method is successfully applied to the determination of streptomycin from pharmaceutical preparation.

引用

页码：881 / 892

页数：12

共 17 条

[1] PREPARATIVE LIQUID-CHROMATOGRAPHY OF PHARMACEUTICALS USING SILICA-GEL WITH AQUEOUS ELUENTS [J].

ADAMOVICS, J ;

UNGER, S .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1986, 9 (01) :141-155

[2]

ALLOWIN J, 1988, J PLANNER CHROMATOGR, V1, P50

[3]

BADAR S, 1991, J CHROMATOGR, V571, P189

[4]

BARDICY E, 1986, J ASSOC OFF ANA CHEM, V69, P173

[5] LIQUID-CHROMATOGRAPHIC DETERMINATION OF PENICILLINS BY POSTCOLUMN ALKALINE-DEGRADATION USING A HOLLOW-FIBER MEMBRANE REACTOR [J].

HAGINAKA, J ;

WAKAI, J .

ANALYTICAL BIOCHEMISTRY, 1988, 168 (01) :132-140

[6]

KIRK RE, 1956, ENCY CHEM TECHNOLOGY, V13, P66

[7] STREPTOMYCIN THERAPY IN NONTUBERCULOUS DISEASES [J].

KITCHEN, HB ;

WAKSMAN, SA .

JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION-SCIENTIFIC EDITION, 1953, 42 (09) :522-536

[8]

Komarova N I, 1991, Farmakol Toksikol, V54, P65

[9]

MASCINI M, 1987, ANAL CHEM, V200, P273

[10]

MIN S, 1991, YAOWU FENXI ZAZHI, V11, P93

← 1 2 →