KINETIC RESOLUTIONS IN ANTIALDOL REACTIONS WITH RACEMIC 2-PHENYLTHIO ALDEHYDES - ASYMMETRIC-SYNTHESIS OF CYCLIC ETHERS AND LACTONES WITH PHENYLTHIO MIGRATION

被引：16

作者：

CHIBALE, K ^{[1
]}

WARREN, S ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,LENSFIELD RD,CAMBRIDGE CB2 1EW,ENGLAND

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(00)74262-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic resolutions in Lewis acid catalysed asymmetric anti aldol reactions of the boron enolate of imide (2) with racemic 2-phenylthio aldehydes (3a) - (3c) give good yields of anti,anti aldols (7). Synthesis of homochiral cyclic ethers (4a) - (4c) and (5a) - (5c), and a simple novel route to homochiral lactones (6a) - (6c) are described.

引用

页码：4369 / 4372

页数：4

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