A CONFIGURATIONAL MODEL FOR SIPHONARIID POLYPROPIONATES DERIVED FROM STRUCTURAL AND BIOSYNTHETIC CONSIDERATIONS

被引：26

作者：

GARSON, MJ ^{[1
]}

GOODMAN, JM ^{[1
]}

PATERSON, I ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 37期

关键词：

D O I：

10.1016/0040-4039(94)85044-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The energies of the acetal ring systems in siphonarin B (2), muamvatin (5), and caloundrin B (7) are compared. A configurational model for siphonariid metabolites is proposed which rationalises the stereochemistry of their acyclic precursors. It contains a tetrapropionate unit common to the Cane-Celmer-Westley PAPA model for polyether antibiotics of bacterial origin.

引用

页码：6929 / 6932

页数：4

共 39 条

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