IMPROVED DEPROTECTION IN SOLID-PHASE PEPTIDE-SYNTHESIS - DEPROTECTION OF NI-FORMYL-TRYPTOPHAN TO TRYPTOPHAN IN LOW CONCENTRATIONS OF HF IN ME2S-P-THIOCRESOL MIXTURES

被引：18

作者：

HEATH, WF ^{[1
]}

TAM, JP ^{[1
]}

MERRIFIELD, RB ^{[1
]}

机构：

[1] ROCKEFELLER UNIV,NEW YORK,NY 10021

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1982年 / 16期

关键词：

D O I：

10.1039/c39820000896

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：896 / 897

页数：2

共 9 条

[1]

ALAKHOV YB, 1970, CHEM COMMUN, P406

[2]

CHINO N, 1978, PEPTIDE CHEM 1977, P27

[3] IMPROVED SOLID-PHASE SYNTHESIS OF TRYPTOPHAN-CONTAINING PEPTIDES .1. USE OF HYDROGEN-CHLORIDE IN FORMIC-ACID AS A REAGENT FOR CLEAVAGE OF TERT BUTYLOXYCARBONYL GROUP [J].

OHNO, M ;

TSUKAMOT.S ;

ZUMIYA, N ;

MAKISUMI, S .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1972, 45 (09) :2852-+

[4]

TAM JP, 1981, TETRAHEDRON LETT, V22, P2851, DOI 10.1016/S0040-4039(01)81767-6

[5]

TAM JP, J AM CHEM SOC

[6]

TAM JP, TETRAHEDRON LETT

[7]

TAM JP, UNPUB INT J PEPT PRO

[8] SYNTHESIS OF [15-LEUCINE]HUMAN-GASTRIN I .3. PURIFICATION OF SYNTHETIC HEPTACOSAPEPTIDE AMIDE [J].

WUNSCH, E ;

SCHARF, R ;

JAEGER, E ;

DEFFNER, M .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1972, 353 (11) :1716-&

[9] PROTECTION OF TRYPTOPHAN WITH FORMYL GROUP IN PEPTIDE SYNTHESIS [J].

YAMASHIRO, D ;

LI, CH .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (15) :2594-2597

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