ISOTEUFLIDIN, A NEO-CLERODANE DITERPENOID FROM TEUCRIUM-CHAMAEDRYS, AND REVISED STRUCTURES OF TEUCRIN-F AND TEUCRIN-G

被引：29

作者：

RODRIGUEZ, MC

BARLUENGA, J

SAVONA, G

PIOZZI, F

SERVETTAZ, O

RODRIGUEZ, B

机构：

[1] UNIV PALERMO, IST CHIM ORGAN, I-90123 PALERMO, ITALY

[2] UNIV MILAN, DEPARTIMENTO BIOL, I-20122 MILAN, ITALY

[3] CSIC, INST QUIM ORGAN, MADRID, SPAIN

来源：

PHYTOCHEMISTRY | 1984年 / 23卷 / 07期

关键词：

D O I：

10.1016/S0031-9422(00)80487-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new neo-clerodane diterpenoid, isoteuflidin, was isolated from the aerial part of T. chamaedrys. Its structure, 15,16-epoxy-3.beta.-hydroxy-19-nor-neo-cleroda-4,13(16), 14-triene-18,6.alpha.:20,12S-diolide, was established mainly by spectroscopic means and by comparison with closely related compounds. In addition, the previously proposed structures for teucrins F and G [15,16-epoxy-4.beta.,7.alpha.-dihydroxy-neo-cleroda-2,13(16),14-triene-18,19:20,12S-diolide and 2.xi.,3.xi.: 15,16-diepoxy-4.beta.,7.xi.-dihydroxy-neo-cleroda-13(16),14-diene-18,19:20,12S-diolide, respectively] were revised establishing that their secondary hydroxyl group must be placed at the C-6.beta. position instead of the C-7 position.

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页码：1465 / 1469

页数：5

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