IDENTIFICATION OF CAFFEINE AND ITS METABOLITES IN HUMAN URINE EXTRACTS BY ELECTRON-IMPACT IONIZATION TANDEM MASS-SPECTROMETRY

被引：12

作者：

LIGUORI, A ^{[1
]}

MASCARO, P ^{[1
]}

PORCELLI, B ^{[1
]}

SINDONA, G ^{[1
]}

UCCELLA, N ^{[1
]}

机构：

[1] UNIV SIENA,FAC MED & CHIRURG,IST CHIM BIOL,I-53100 SIENA,ITALY

来源：

ORGANIC MASS SPECTROMETRY | 1991年 / 26卷 / 06期

关键词：

D O I：

10.1002/oms.1210260613

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxanthine and 7-methylxanthine) were characterized by tandem mass spectrometry. The direct analysis of human urinary extracts by tandem mass spectrometry allows the unambiguous identification of caffeine and its metabolites present simultaneously in the urine.

引用

页码：608 / 612

页数：5

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