SYNTHESIS AND RESOLUTION OF PUTATIVE DIASTEREOMERIC N(2)-DEOXYGUANOSINE AND N(6)-DEOXYADENOSINE ADDUCTS OF BIOLOGICALLY-ACTIVE CYCLOPENTAPAH

被引：10

作者：

SANGAIAH, R

GOLD, A

BALL, LM

MATTHEWS, DL

TONEY, GE

机构：

[1] Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill

[2] NIEHS, Research Triangle Park

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(00)61124-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of the putative DNA adducts from 1,2-dihydroaceanthrylene-1,2-oxide and the exocyclic amino groups of deoxyguanosine and deoxyadenosine and from 3,4-dihydrocyclopenta[cd]pyrene and the exocyclic amino group of deoxyguanosine is reported.

引用

页码：5487 / 5490

页数：4

共 10 条

[1] SYNTHESIS OF N-6-ADENOSINE ADDUCTS EXPECTED FROM CYCLOPENTA-RING ACTIVATION OF ACENAPHTHYLENE AND ACEANTHRYLENE [J].

BARTCZAK, AW ;

SANGAIAH, R ;

KELMAN, DJ ;

TONEY, GE ;

DETERDING, LJ ;

CHARLES, J ;

MARBURY, GD ;

GOLD, A .

TETRAHEDRON LETTERS, 1989, 30 (25) :3251-3254

[2] P-32-ADDUCT ASSAY - COMPARATIVE RECOVERIES OF STRUCTURALLY DIVERSE DNA ADDUCTS IN THE VARIOUS ENHANCEMENT PROCEDURES [J].

GUPTA, RC ;

EARLEY, K .

CARCINOGENESIS, 1988, 9 (09) :1687-1693

[3] NEW STRATEGY FOR THE SYNTHESIS OF OLIGODEOXYNUCLEOTIDES BEARING ADDUCTS AT EXOCYCLIC AMINO SITES OF PURINE NUCLEOSIDES [J].

HARRIS, CM ;

ZHOU, L ;

STRAND, EA ;

HARRIS, TM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (11) :4328-4329

[4] THE PARA-NITROPHENYLETHYL (NPE) GROUP - A VERSATILE NEW BLOCKING GROUP FOR PHOSPHATE AND AGLYCONE PROTECTION IN NUCLEOSIDES AND NUCLEOTIDES [J].

HIMMELSBACH, F ;

SCHULZ, BS ;

TRICHTINGER, T ;

CHARUBALA, R ;

PFLEIDERER, W .

TETRAHEDRON, 1984, 40 (01) :59-72

[5] ALPHA-THYMIDIN [J].

HOFFER, M .

CHEMISCHE BERICHTE-RECUEIL, 1960, 93 (12) :2777-2781

[6] SYNTHESES OF POLYCYCLIC AROMATIC HYDROCARBON-NUCLEOSIDE AND OLIGONUCLEOTIDE ADDUCTS SPECIFICALLY ALKYLATED ON THE AMINO FUNCTIONS OF DEOXYGUANOSINE AND DEOXYADENOSINE [J].

LEE, H ;

HINZ, M ;

STEZOWSKI, JJ ;

HARVEY, RG .

TETRAHEDRON LETTERS, 1990, 31 (47) :6773-6776

[7]

McManus S. P., 1973, SYNTHETIC COMMUN, V3, P177

[8] DIOXIRANES - SYNTHESIS AND REACTIONS OF METHYLDIOXIRANES [J].

MURRAY, RW ;

JEYARAMAN, R .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (16) :2847-2853

[9] DNA ADDUCT FORMATION, METABOLISM, AND MORPHOLOGICAL TRANSFORMING ACTIVITY OF ACEANTHRYLENE IN C3H10T1/2CL8 CELLS [J].

NESNOW, S ;

ROSS, J ;

MOHAPATRA, N ;

GOLD, A ;

SANGAIAH, R ;

GUPTA, R .

MUTATION RESEARCH, 1989, 222 (03) :223-235

[10]

ROBINS MJ, 1978, NUCLEIC ACID CHEM, P601

← 1 →