THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CERTAIN 4'-THIONUCLEOSIDES

被引:27
作者
SECRIST, JA [1 ]
PARKER, WB [1 ]
TIWARI, KN [1 ]
MESSINI, L [1 ]
SHADDIX, SC [1 ]
ROSE, LM [1 ]
BENNETT, LL [1 ]
MONTGOMERY, JA [1 ]
机构
[1] SO RES INST,DEPT BIOL CHEM,BIRMINGHAM,AL 35205
来源
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期
关键词
D O I
10.1080/15257779508012449
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Results are presented on the synthesis and biological activity of several types of 4'-thionucleosides as potential anticancer agents. Detailed studies on the mechanism of action of 4'-thiothymidine are also presented.
引用
收藏
页码:675 / 686
页数:12
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