FUNCTION OF MYOCARDIAL MITOCHONDRIA IN ADRIAMYCIN-INDUCED CARDIOMYOPATHY OF RABBITS

被引：28

作者：

BIER, CC ^{[1
]}

JAENKE, RS ^{[1
]}

机构：

[1] COLORADO STATE UNIV, COLL VET MED & BIOMED SCI, DEPT PATHOL, FT COLLINS, CO 80523 USA

来源：

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE | 1976年 / 57卷 / 05期

关键词：

D O I：

10.1093/jnci/57.5.1091

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Ultrastructural examination of the myocardia of New Zealand White rabbits showed progressive cardiomyopathy with prominent mitochondrial lesions after 56 days of increased doses of the antitumor agent adriamycin. During all phases of study, similar respiratory control rates and ADP:O ratios were found in myocardial mitochondria isolated form adriamycin-treated and control rabbits.

引用

页码：1091 / 1094

页数：4

共 28 条

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[6] 2-M
[7] CLINICAL EVALUATION OF ADRIAMYCIN, A NEW ANTITUMOUR ANTIBIOTIC
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[10] 2-A

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