Point-to-point observations of a gaseous nebula correspond to an integration over regions with different physical conditions. Therefore, observational data may vary from point to point and may differ from data for the whole nebula. Thus, an analysis of high spatial resolution data requires line-of-sight results from a given set of photoionization models. This paper presents results for several useful line-of-sight quantities related to H II regions, such as line intensity ratios, ionic column densities, and temperature fluctuation, t2. The value of t2 obtained from the models depends on the considered ion, gas abundance, gas density, and stellar temperature, as well as on the considered line of sight. Based on these results, a comparison between abundances obtained from empirical methods and those adopted in the models shows that the appropriated value of t2 must be used in any empirical abundance determination, especially when discussing abundance variations across a given nebula.