HUMORAL-FACTORS DERIVED FROM GLIAL-CELLS PROTECT CULTURED NEUROBLASTOMA-CELLS AGAINST GLUTAMATE TOXICITY

被引：14

作者：

AMANO, S ^{[1
]}

OHASHI, M ^{[1
]}

ISHIKO, T ^{[1
]}

HAZAMA, F ^{[1
]}

机构：

[1] SHIGA UNIV MED SCI,DEPT NEUROSURG,OTSU,SHIGA 52021,JAPAN

来源：

BRAIN RESEARCH | 1994年 / 645卷 / 1-2期

关键词：

NEURONAL CELL; ASTROCYTE; CULTURE SYSTEM; HUMORAL FACTOR; GLUTAMATE; CYTOTOXICITY; PROTECTION;

D O I：

10.1016/0006-8993(94)91672-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The protective effects of glial cells against glutamate cytotoxicity on neuronal cells were studied using clonal neuroblastoma cells and two types of glial cells. Neuronal cells treated with glia-conditioned medium became able to tolerate glutamate toxicity. It is suggested that the preparatory processes against glutamate toxicity might be developed in neurons by the humoral factor(s) released from glial cells.

引用

页码：347 / 350

页数：4

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