MULTIPLE-SCLEROSIS IN THE SPINAL-CORD - MR APPEARANCE AND CORRELATION WITH CLINICAL-PARAMETERS

被引:203
作者
TARTAGLINO, LM
FRIEDMAN, DP
FLANDERS, AE
LUBLIN, FD
KNOBLER, RL
LIEM, M
机构
[1] THOMAS JEFFERSON UNIV HOSP,CTR MULTIPLE SCLEROSIS,DEPT NEUROL,PHILADELPHIA,PA 19107
[2] RADIOL ASSOCIATES SARASOTA,SARASOTA,FL
关键词
NERVOUS SYSTEM; DISEASES; SCLEROSIS; MULTIPLE; SPINAL CORD; MR;
D O I
10.1148/radiology.195.3.7754002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To determine the characteristic magnetic resonance (MR) imaging features of multiple sclerosis (MS) that affect the spinal cord. MATERIALS AND METHODS: Sixty-eight patients underwent MR imaging of the cervical and/or thoracic spine. Plaques were analyzed for lesion length, cross-sectional area and location, signal intensity, and morphology. The clinical parameters of MS type, duration of disease, sex, and age were also correlated with these MR imaging findings. RESULTS: One hundred twenty-four demyelinating plaques were found in these 68 patients; 38 had more than one plaque. The majority of plaques were two body segments in length or less and peripherally located, and occupied less than 50% of the cross-sectional area of the cord. Plaques associated with cord atrophy were more likely to occur with the relapsing-progressive form of MS. Cord swelling was found only in the relapsing-remitting form of MS. CONCLUSION: Spinal cord MS plaques are characteristically peripherally located, are less than two vertebral segments in length, and occupy less than half the cross-sectional area of the cord.
引用
收藏
页码:725 / 732
页数:8
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