ANALYSIS OF A MUTANT STRAIN OF HUMAN FIBROBLASTS WITH A DEFECT IN INTERNALIZATION OF RECEPTOR-BOUND LOW-DENSITY LIPOPROTEIN

被引：192

作者：

BROWN, MS ^{[1
]}

GOLDSTEIN, JL ^{[1
]}

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT INTERNAL MED,DIV MED GENET,DALLAS,TX 75235

来源：

CELL | 1976年 / 9卷 / 04期

关键词：

D O I：

10.1016/0092-8674(76)90130-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：663 / 674

页数：12

共 25 条

[1] LOCALIZATION OF LOW-DENSITY LIPOPROTEIN RECEPTORS ON PLASMA-MEMBRANE OF NORMAL HUMAN FIBROBLASTS AND THEIR ABSENCE IN CELLS FROM A FAMILIAL HYPERCHOLESTEROLEMIA HOMOZYGOTE
ANDERSON, RGW
GOLDSTEIN, JL
BROWN, MS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (07) : 2434 - 2438
[2] DEGRADATION OF CATIONIZED LOW-DENSITY LIPOPROTEIN AND REGULATION OF CHOLESTEROL-METABOLISM IN HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA FIBROBLASTS
BASU, SK
GOLDSTEIN, JL
ANDERSON, RGW
BROWN, MS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (09) : 3178 - 3182
[3] BIERMAN EL, 1974, CIRC RES, V35, P136, DOI 10.1161/01.RES.35.1.136
[4] HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA - POSSIBLE BIOCHEMICAL EXPLANATION OF CLINICAL HETEROGENEITY
BRESLOW, JL
SPAULDING, DR
LUX, SE
LEVY, RI
LEES, RS
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1975, 293 (18) : 900 - 903
[5] BROWN M, IN PRESS
[6] BROWN MS, 1974, J BIOL CHEM, V249, P789
[7] FAMILIAL HYPERCHOLESTEROLEMIA - DEFECTIVE BINDING OF LIPOPROTEINS TO CULTURED FIBROBLASTS ASSOCIATED WITH IMPAIRED REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY
BROWN, MS
GOLDSTEIN, JL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (03) : 788 - 792
[8] RECEPTOR-MEDIATED CONTROL OF CHOLESTEROL-METABOLISM
BROWN, MS
GOLDSTEIN, JL
[J]. SCIENCE, 1976, 191 (4223) : 150 - 154
[9] BROWN MS, 1976, NEW ENGL J MED, V294, P1386
[10] REGULATION OF ACTIVITY OF LOW-DENSITY LIPOPROTEIN RECEPTOR IN HUMAN FIBROBLASTS
BROWN, MS
GOLDSTEIN, JL
[J]. CELL, 1975, 6 (03) : 307 - 316

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