NALTREXONE BLOCKS THE EFFECTS OF PRENATAL STRESS ON SEXUAL-BEHAVIOR DIFFERENTIATION IN MALE-RATS

被引：58

作者：

WARD, OB ^{[1
]}

MONAGHAN, EP ^{[1
]}

WARD, IL ^{[1
]}

机构：

[1] VILLANOVA UNIV, DEPT PSYCHOL, VILLANOVA, PA 19085 USA

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1986年 / 25卷 / 03期

关键词：

D O I：

10.1016/0091-3057(86)90143-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The male offspring of rats stressed three times during days 14-21 of pregnancy were more likely to show lordotic behavior when tested in adulthood than were control males. This feminization of sexual behavior was not observed if the mothers were injected with the opioid antagonist naltrexone before being stressed. These data suggest that endogenous opioids released with the opioid antagonist naltrexone before being stressed. These data suggest that endogenous opioids released under conditions of stress can alter the normal process of sexual behavior differentiation in the fetal male rat.

引用

页码：573 / 576

页数：4

共 36 条

[1] STATISTICAL PROCEDURE IN DEVELOPMENTAL STUDIES ON SPECIES WITH MULTIPLE OFFSPRING [J].