THE HUMAN T-CELL ANTIGEN RECEPTOR IS ENCODED BY VARIABLE, DIVERSITY, AND JOINING GENE SEGMENTS THAT REARRANGE TO GENERATE A COMPLETE V-GENE

被引：286

作者：

SIU, G ^{[1
]}

CLARK, SP ^{[1
]}

YOSHIKAI, Y ^{[1
]}

MALISSEN, M ^{[1
]}

YANAGI, Y ^{[1
]}

STRAUSS, E ^{[1
]}

MAK, TW ^{[1
]}

HOOD, L ^{[1
]}

机构：

[1] UNIV TORONTO,ONTARIO CANC INST,DEPT MED BIOPHYS,TORONTO M4X 1K9,ONTARIO,CANADA

来源：

CELL | 1984年 / 37卷 / 02期

关键词：

D O I：

10.1016/0092-8674(84)90369-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：393 / 401

页数：9

共 41 条

[1] THE HUMAN T-CELL RECEPTOR - APPEARANCE IN ONTOGENY AND BIOCHEMICAL RELATIONSHIP OF ALPHA-SUBUNITS AND BETA-SUBUNITS ON IL-2 DEPENDENT CLONES AND T-CELL TUMORS [J].

ACUTO, O ;

HUSSEY, RE ;

FITZGERALD, KA ;

PROTENTIS, JP ;

MEUER, SC ;

SCHLOSSMAN, SF ;

REINHERZ, EL .

CELL, 1983, 34 (03) :717-726

[2]

ACUTO O, 1984, P NAT ACAD SCI US

[3] JOINING OF IMMUNOGLOBULIN HEAVY-CHAIN GENE SEGMENTS - IMPLICATIONS FROM A CHROMOSOME WITH EVIDENCE OF 3 D-JH FUSIONS [J].

ALT, FW ;

BALTIMORE, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (13) :4118-4122

[4] IS TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE A SOMATIC MUTAGEN IN LYMPHOCYTES [J].

BALTIMORE, D .

NATURE, 1974, 248 (5447) :409-411

[5] EVOLUTION OF IMMUNOGLOBULIN-V GENES - EVIDENCE INDICATING THAT RECENTLY DUPLICATED HUMAN-VK SEQUENCES HAVE DIVERGED BY GENE CONVERSION [J].

BENTLEY, DL ;

RABBITTS, TH .

CELL, 1983, 32 (01) :181-189

[6] HUMAN-IMMUNOGLOBULIN VARIABLE REGION GENES - DNA SEQUENCES OF 2 V-KAPPA-GENES AND A PSEUDOGENE [J].

BENTLEY, DL ;

RABBITTS, TH .

NATURE, 1980, 288 (5792) :730-733

[7] DNA-SEQUENCES OF THE JOINING REGIONS OF MOUSE LAMBDA-LIGHT CHAIN IMMUNOGLOBULIN GENES [J].

BLOMBERG, B ;

TONEGAWA, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (02) :530-533

[8] HEAVY-CHAIN VARIABLE REGION CONTRIBUTION TO THE NPB FAMILY OF ANTIBODIES - SOMATIC MUTATION EVIDENT IN A GAMMA-2A VARIABLE REGION [J].

BOTHWELL, ALM ;

PASKIND, M ;

RETH, M ;

IMANISHIKARI, T ;

RAJEWSKY, K ;

BALTIMORE, D .

CELL, 1981, 24 (03) :625-637

[9]

BREATHNACH R, 1981, ANNU REV BIOCHEM, V50, P349, DOI 10.1146/annurev.bi.50.070181.002025

[10] A SINGLE VH GENE SEGMENT ENCODES THE IMMUNE-RESPONSE TO PHOSPHORYLCHOLINE - SOMATIC MUTATION IS CORRELATED WITH THE CLASS OF THE ANTIBODY [J].

CREWS, S ;

GRIFFIN, J ;

HUANG, H ;

CALAME, K ;

HOOD, L .

CELL, 1981, 25 (01) :59-66

← 1 2 3 4 5 →