MONOSOMY-12P IN A RADIATION-INDUCED GERM-CELL TUMOR

被引：10

作者：

COWAN, JM ^{[1
]}

BECKETT, MA ^{[1
]}

TARBELL, NJ ^{[1
]}

WEICHSELBAUM, RR ^{[1
]}

机构：

[1] CHILDRENS HOSP MED CTR, BOSTON, MA 02115 USA

来源：

GENES CHROMOSOMES & CANCER | 1990年 / 2卷 / 03期

关键词：

D O I：

10.1002/gcc.2870020304

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report results of cytogenetic analysis of a cell line established from a radiation induced germ cell tumor. Tumors of this type are rare, and there is only one other report of chromosome analyses of solid tumors induced by radiotherapy (Cowan et al., 1990). The cells were grown for over a year, and harvested at passage 13. The karyotype was pseudodiploid, with several balanced translocations. Spontaneously occurring germ cell tumors are associated with i(12p). We did not observe an i(12p), but instead found monosomy of 12p and 7q22→q32. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：186 / 190

页数：5

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