LONG-LASTING ANTICONVULSANT EFFECTS OF DIAZEPAM IN DIFFERENT MOUSE STRAINS - CORRELATIONS WITH BRAIN CONCENTRATIONS AND RECEPTOR OCCUPANCY

被引：29

作者：

FILE, SE

GREENBLATT, DJ

MARTIN, IL

BROWN, C

机构：

[1] TUFTS UNIV,NEW ENGLAND MED CTR,DIV CLIN PHARMACOL,BOSTON,MA 02111

[2] MRC,NEUROCHEM PHARMACOL UNIT,CAMBRIDGE,ENGLAND

来源：

PSYCHOPHARMACOLOGY | 1985年 / 86卷 / 1-2期

关键词：

D O I：

10.1007/BF00431698

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：137 / 141

页数：5

共 10 条

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[3] INVIVO RECEPTOR OCCUPATION BY BENZODIAZEPINES AND CORRELATION WITH THE PHARMACOLOGICAL EFFECT
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[J]. BRAIN RESEARCH, 1979, 179 (01) : 147 - 156
[4] STRAIN DIFFERENCES IN MICE IN THE DEVELOPMENT OF TOLERANCE TO THE ANTI-PENTYLENETETRAZOLE EFFECTS OF DIAZEPAM
FILE, SE
[J]. NEUROSCIENCE LETTERS, 1983, 42 (01) : 95 - 98
[5] GARATTINI S, 1973, BENZODIAZEPINES, P75
[6] ENTRY OF DIAZEPAM AND ITS MAJOR METABOLITE INTO CEREBROSPINAL-FLUID
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[7] ANALYSIS OF LORAZEPAM AND ITS GLUCURONIDE METABOLITE BY ELECTRON-CAPTURE GAS-LIQUID-CHROMATOGRAPHY - USE IN PHARMACOKINETIC STUDIES OF LORAZEPAM
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[8] AUDIOGENIC-SEIZURES IN DBA/2 MICE DISCRIMINATE SENSITIVELY BETWEEN LOW EFFICACY BENZODIAZEPINE RECEPTOR AGONISTS AND INVERSE AGONISTS
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[J]. LIFE SCIENCES, 1983, 33 (04) : 393 - 399
[9] METHODS FOR THE DETERMINATION OF LORAZEPAM AND CHLORDIAZEPOXIDE AND METABOLITES IN BRAIN-TISSUE - A COMPARISON WITH PLASMA-CONCENTRATIONS IN THE RAT
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ABERNETHY, DR
GREENBLATT, DJ
FILE, SE
[J]. JOURNAL OF CHROMATOGRAPHY, 1983, 277 (OCT): : 201 - 208
[10] CORRELATION BETWEEN BENZODIAZEPINE RECEPTOR OCCUPATION AND ANTICONVULSANT EFFECTS OF DIAZEPAM
PAUL, SM
SYAPIN, PJ
PAUGH, BA
MONCADA, V
SKOLNICK, P
[J]. NATURE, 1979, 281 (5733) : 688 - 689

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