PHYSICAL MAP AROUND THE RETINOBLASTOMA GENE - POSSIBLE GENOMIC IMPRINTING SUGGESTED BY NRUI DIGESTION

被引：15

作者：

BLANQUET, V

TURLEAU, C

DEGROUCHY, J

CREAUGOLDBERG, N

机构：

[1] U. 173 INSERM, Hôpital Necker-Enfants-Malades, 75743 Paris Cedex 15, 149, rue de Sèvres

来源：

GENOMICS | 1991年 / 10卷 / 02期

关键词：

D O I：

10.1016/0888-7543(91)90319-A

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A long-range restriction map constructed around the retinoblastoma (RB) gene by means of PFGE analysis allowed further definition of chromosomal rearrangements with a breakpoint within the gene, as well as of submicroscopic deletions. A serendipitous observation was that the NruI restriction pattern differs according to the parental orgin of the rearrangement. © 1991.

引用

页码：350 / 355

页数：6

共 14 条

[1]

BLANQUET V, 1987, HUM GENET, V76, P102

[2]

BLANQUET V, 1991, IN PRESS AM J MED GE, V39

[3] HUMAN RETINOBLASTOMA GENE - LONG-RANGE MAPPING AND ANALYSIS OF ITS DELETION IN A BREAST-CANCER CELL-LINE [J].