POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDER - INTRATHORACIC MANIFESTATIONS

被引:87
作者
DODD, GD [1 ]
LEDESMAMEDINA, J [1 ]
BARON, RL [1 ]
FUHRMAN, CR [1 ]
机构
[1] CHILDRENS HOSP PITTSBURGH,DEPT RADIOL,PITTSBURGH,PA
关键词
HEART; TRANSPLANTATION; KIDNEY; LIVER; LUNG; NODULE; LYMPHOMA; CT;
D O I
10.1148/radiology.184.1.1609104
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation and immunosuppression. Early diagnosis and treatment greatly affect prognosis. Chest radiographs (n = 13), chest computed tomographic (CT) scans (n = 2), or both (n = 20) from 35 patients with intrathoracic PTLD were retrospectively studied to define the intrathoracic manifestations of this disorder. Intrathoracic abnormalities consisted of pulmonary nodules (16 patients), patchy air-space consolidation (three patients), mediastinal and hilar adenopathy (17 patients), thymic enlargement (two patients), pericardial thickening and/or effusions (two patients), and pleural effusions (four patients). Multiple, well-circumscribed pulmonary nodules with or without mediastinal adenopathy are highly suggestive of PTLD. However, pathologic examination is usually necessary for a definitive diagnosis.
引用
收藏
页码:65 / 69
页数:5
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