POLYCHLORINATED-BIPHENYLS, CLASSIFIED AS EITHER PHENOBARBITAL-TYPE OR 3-METHYLCHOLANTHRENE-TYPE INDUCERS OF CYTOCHROME-P-450, ARE BOTH HEPATIC TUMOR PROMOTERS IN DIETHYLNITROSAMINE-INITIATED RATS

被引：49

作者：

BUCHMANN, A

KUNZ, W

WOLF, CR

OESCH, F

ROBERTSON, LW

机构：

[1] GERMAN CANC RES CTR, INST BIOCHEM, NEUENHEIMER FELD 280, D-6900 HEIDELBERG, GERMANY

[2] UNIV MAINZ, INST TOXICOL, D-6500 MAINZ, GERMANY

[3] UNIV EDINBURGH, DEPT CHEM, IMPERIAL CANC RES FUND, MOLEC PHARMACOL & DRUG METAB LAB, EDINBURGH EH8 9XD, SCOTLAND

来源：

CANCER LETTERS | 1986年 / 32卷 / 03期

关键词：

D O I：

10.1016/0304-3835(86)90176-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：243 / 253

页数：11

共 33 条

[1] BINDING OF POLYCHLORINATED-BIPHENYLS CLASSIFIED AS EITHER PHENOBARBITONE-TYPE, 3-METHYLCHOLANTHRENE-TYPE OR MIXED-TYPE INDUCERS TO CYTOSOLIC AH RECEPTOR [J].

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[2] REGULATION AND EXPRESSION OF 4 CYTOCHROME-P-450 ISOENZYMES, NADPH-CYTOCHROME-P-450 REDUCTASE, THE GLUTATHIONE TRANSFERASE-B AND TRANSFERASE-C AND MICROSOMAL EPOXIDE HYDROLASE IN PRENEOPLASTIC AND NEOPLASTIC LESIONS IN RAT-LIVER [J].

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[3]

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[4] THE DISPOSITION AND THE LIVER AND THYMUS GLAND TOXICITY OF 3,3',4,4'-TETRACHLOROBIPHENYL IN THE FEMALE RAT [J].

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[5] CORRELATION BETWEEN PROMOTION OF ENZYME-DEFICIENT ISLANDS AND INDUCTION OF MONOOXYGENASE ACTIVITIES BY HALOGENATED HYDROCARBONS IN RAT-LIVER [J].

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[6] POLYBROMINATED BIPHENYLS AS PROMOTERS IN EXPERIMENTAL HEPATOCARCINOGENESIS IN RATS [J].

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AUST, SD ;

TROSKO, JE .

CARCINOGENESIS, 1982, 3 (10) :1183-1186

[7] EFFECT OF VARYING THE LENGTH OF EXPOSURE TO POLYBROMINATED BIPHENYLS ON THE DEVELOPMENT OF GAMMA-GLUTAMYL-TRANSFERASE TRANSPEPTIDASE ENZYME-ALTERED FOCI [J].

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AUST, SD .

CARCINOGENESIS, 1984, 5 (01) :63-66

[8] HEPATIC TUMOR-PROMOTING ABILITY OF 3,3',4,4',5,5'-HEXABROMOBIPHENYL - THE INTERRELATIONSHIP BETWEEN TOXICITY, INDUCTION OF HEPATIC-MICROSOMAL DRUG-METABOLIZING-ENZYMES, AND TUMOR-PROMOTING ABILITY [J].

JENSEN, RK ;

SLEIGHT, SD ;

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TROSKO, JE .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1983, 71 (02) :163-176

[9] INDUCTION OF LIVER TUMORS IN SHERMAN STRAIN FEMALE RATS BY POLYCHLORINATED BIPHENYL AROCLOR 1260 [J].

KIMBROUGH, RD ;

SQUIRE, RA ;

LINDER, RE ;

STRANDBERG, JD ;

MONTALI, RJ ;

BURSE, VW .

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[10]

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