ASYMMETRIC METAL CARBENE INSERTION INTO THE SI-H BOND

被引：49

作者：

LANDAIS, Y

PLANCHENAULT, D

机构：

[1] Institut de Chimie Organique, Université de Lausanne, 1005 Lausanne, Rue de la Barre

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(00)60729-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Silyl-alpha-substituted acetic esters have been prepared in good yields and reasonable diastereoselectivities using an asymmetric metal carbene insertion into the Si-H bond. Optically active 1,2-diols were then prepared after reduction of the ester and conversion of the C-Si bond into a C-OH bond.

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页码：4565 / 4568

页数：4

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