OPTICAL PURIFICATION OF CHIRAL GLYCIDYL ARENESULFONATES

被引：4

作者：

ANANTH, R ^{[1
]}

CHEN, J ^{[1
]}

SHUM, W ^{[1
]}

机构：

[1] ARCO CHEM CO,NEWTOWN SQ,PA 19073

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 02期

关键词：

D O I：

10.1016/0957-4166(95)00002-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The melting point phase diagrams of glycidyl tosylate (1), glycidyl 3-nitrobenzenesulfonate (2), and trans-3-methylglycidyl tosylate (3) have been investigated. Compounds 1 and 2 are found to exhibit a more significant solid solution behavior in the terminal zones of the phase diagram than 3, and are therefore more difficult to enrich enantiomerically by recrystallizations. The crystallization of 2 in ethanol is further complicated by polymorphism which can be followed by differential scanning calorimetry. The effects of these properties on the optical purification of 1-3 are discussed.

引用

页码：317 / 320

页数：4

共 7 条

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