SYNTHESIS AND ENZYMATIC-ACTIVITY OF 1,2,4-TRIAZOLE-3-CARBOXAMIDE 6'-DEOXYHOMORIBONUCLEOSIDE-6'-PHOSPHONIC ACID AND RELATED COMPOUNDS

被引：21

作者：

FUERTES, M ^{[1
]}

WITKOWSK.JT ^{[1
]}

STREETER, DG ^{[1
]}

ROBINS, RK ^{[1
]}

机构：

[1] ICN PHARM INC,NUCLEIC ACID RES INST,IRVINE,CA 92664

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1974年 / 17卷 / 06期

关键词：

D O I：

10.1021/jm00252a015

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：642 / 645

页数：4

共 20 条

[1]

BLOCH A, 1973, DRUG DESIGN, V4, pCH8

[2]

CLAYTON SJ, 1968, SYNTHETIC PROCEDURES, V1

[3] SPECIFIC BINDING TO ADENYLOSUCCINATE SYNTHETASE OF ANALOGS OF INOSINIC ACID WITH NITROGEN, SULFUR, AND CARBON SUBSTITUTED FOR PHOSPHATE OXYGENS [J].

HAMPTON, A .

BIOCHIMICA ET BIOPHYSICA ACTA, 1970, 198 (03) :594-&

[4] SYNTHESIS OF 6'-CYANO-6'-DEOXYHOMOADENOSINE-6'-PHOSPHONIC ACID AND ITS PHOSPHORYL AND PYROPHOSPHORYL ANHYDRIDES AND STUDIES OF THEIR INTERACTIONS WITH ADENINE-NUCLEOTIDE UTILIZING ENZYMES [J].

HAMPTON, A ;

SASAKI, T ;

PAUL, B .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (13) :4404-4414

[5] SYNTHESIS OF HOMOADENOSINE-6'-PHOSPHONIC ACID AND STUDIES OF ITS SUBSTRATE AND INHIBITOR PROPERTIES WITH ADENOSINE-MONOPHOSPHATE UTILIZING ENZYMES [J].

HAMPTON, A ;

PERINI, F ;

HARPER, PJ .

BIOCHEMISTRY, 1973, 12 (09) :1730-1736

[6] ANALOGS OF INOSINE 5'-PHOSPHATE WITH PHOSPHORUS - NITROGEN AND PHOSPHORUS - SULFUR BONDS . BINDING AND KINETIC STUDIES WITH INOSINE 5'-PHOSPHATE DEHYDROGENASE [J].

HAMPTON, A ;

BROX, LW ;

BAYER, M .

BIOCHEMISTRY, 1969, 8 (06) :2303-&

[7] IN-VITRO EFFECT OF 1-BETA-D-RIBOFURANOSYL-1,2,4-TRIAZOLE-3-CARBOXAMIDE (VIRAZOLE, ICN-1229) ON DEOXYRIBONUCLEIC ACID AND RIBONUCLEIC-ACID VIRUSES [J].

HUFFMAN, JH ;

SIDWELL, RW ;

KHARE, GP ;

WITKOWSKI, JT ;

ALLEN, LB ;

ROBINS, RK .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1973, 3 (02) :235-241

[8] SYNTHESIS OF 6'-DEOXYHOMONUCLEOSIDE-6'-PHOSPHONIC ACIDS [J].

JONES, GH ;

MOFFATT, JG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (19) :5337-&

[9]

JONES GH, 1968, TETRAHEDRON LETT, P5731

[10] EPIMERIZATION IN PREPARATION OF PURINE NUCLEOSIDES BY FUSION REACTION [J].

MONTGOMERY, JA ;

THORPE, MC ;

LASETER, AG ;

HEWSON, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (20) :7176-+

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