ERYTHRO-SELECTIVE ALDOL CONDENSATION OF AMINE FREE 2-T-BUTYL-5-METHYL-2-PHENYL-1,3-DIOXOLAN-4-ONE LITHIUM ENOLATE SYNTHESIS OF THE ETHYL ACETOLACTATE ENANTIOMERS

被引：20

作者：

GREINER, A

ORTHOLAND, JY

机构：

[1] Rhône Poulenc Agrochimie, Centre de Recherches de la Dargoire, 69263 Lyon Cedex 09

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 14期

关键词：

D O I：

10.1016/S0040-4039(00)74171-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Generated by halogen metal exchange, the sterically hindered 2-t-butyl-5-methyl-2-phenyl -1,3-dioxolan-4-one lithium enolate reacts in an erythroselective way with acetaldehyde. Separation of the resulting diastereomers, followed by alcoholysis lead to the corresponding enantiomerically pure diols.

引用

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页码：1897 / 1900

页数：4

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