NEW ORALLY-ACTIVE SERINE-PROTEASE INHIBITORS

被引：38

作者：

SENOKUCHI, K ^{[1
]}

NAKAI, H ^{[1
]}

NAKAYAMA, Y ^{[1
]}

ODAGAKI, Y ^{[1
]}

SAKAKI, K ^{[1
]}

KATO, M ^{[1
]}

MARUYAMA, T ^{[1
]}

MIYAZAKI, T ^{[1
]}

ITO, H ^{[1
]}

KAMIYASU, K ^{[1
]}

KIM, S ^{[1
]}

KAWAMURA, M ^{[1
]}

HAMANAKA, N ^{[1
]}

机构：

[1] ONO PHARMACEUT CO LTD,MINASE RES INST,OSAKA 618,JAPAN

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1995年 / 38卷 / 14期

关键词：

D O I：

10.1021/jm00014a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2521 / 2523

页数：3

共 12 条

[1]

MARESGUI.M, 1967, J BIOL CHEM, V242, P5782

[2]

MARKWARD.F, 1972, ACTA BIOL MED GER, V28, pK19

[3] A PREDICTED TERTIARY STRUCTURE OF A THROMBIN INHIBITOR-TRYPSIN COMPLEX EXPLAINS THE MECHANISMS OF THE SELECTIVE-INHIBITION OF THROMBIN, FACTOR-XA, PLASMIN, AND TRYPSIN [J].

MATSUZAKI, T ;

SASAKI, C ;

UMEYAMA, H .

JOURNAL OF BIOCHEMISTRY, 1988, 103 (03) :537-543

[4] EFFECTS OF E-3123, A NEW PROTEASE INHIBITOR, ON SEVERAL PROTEASE ACTIVITIES AND ON EXPERIMENTAL ACUTE-PANCREATITIS [J].

MIYAMOTO, K ;

HISHINUMA, I ;

NAGAKAWA, J ;

NAGAOKA, N ;

YAMANAKA, T ;

WAKABAYASHI, T .

FOLIA PHARMACOLOGICA JAPONICA, 1988, 91 (05) :285-293

[5]

MUMFORD RA, 1980, J BIOL CHEM, V255, P2227

[6]

NAKAJIMA K, 1979, J BIOL CHEM, V254, P4027

[7] PHARMACOLOGICAL STUDIES ON 6-AMIDINO-2-NAPHTHYL[4-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO] BENZOATE DIMETHANE SULFONATE (FUT-187) .1. INHIBITORY ACTIVITIES ON VARIOUS KINDS OF ENZYMES INVITRO AND ANTICOMPLEMENT ACTIVITY INVIVO [J].

ODA, M ;

INO, Y ;

NAKAMURA, K ;

KURAMOTO, S ;

SHIMAMURA, K ;

IWAKI, M ;

FUJII, S .

JAPANESE JOURNAL OF PHARMACOLOGY, 1990, 52 (01) :23-34

[8] FOY - [ETHYL PARA-(6-GUANIDINOHEXANOYLOXY) BENZOATE] METHANESULFONATE AS A SERINE PROTEINASE-INHIBITOR .1. INHIBITION OF THROMBIN AND FACTOR-XA INVITRO [J].

OHNO, H ;

KOSAKI, G ;

KAMBAYASHI, J ;

IMAOKA, S ;

HIRATA, F .

THROMBOSIS RESEARCH, 1980, 19 (4-5) :579-588

[9]

OTSUKI M, 1989, BIOMED RES-TOKYO, V10, P25

[10]

SASAKI I, 1989, BIOMED RES-TOKYO, V10, P167

← 1 2 →